The USCBL, currently coordinated by Handicap International, is a coalition of thousands of people and U.S. non-governmental organizations working to: (1) ensure no U.S. use, production, or transfer of antipersonnel landmines and cluster munitions; (2) encourage the U.S. to join the 1997 Mine Ban Treaty and the 2008 Convention on Cluster Munitions; and (3) secure high levels of U.S. government support for clearance and assistance programs for victims of landmines, cluster munitions and other explosive remnants of war.

The USCBL is the U.S. affiliate of the International Campaign to Ban Landmines (ICBL)—the co-laureate of the 1997 Nobel Peace Prize—and is a member of the Cluster Munition Coalition, an international coalition working to protect civilians from the effects of cluster munitions by promoting universal adherence to and full implementation of the Convention on Cluster Munitions.